Predictive value of early postoperative IOP and bleb morphology
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چکیده
Our aim was to determine the predictive value of postoperative Background bleb morphological features and intraocular pressure (IOP) on the success rate of trabeculectomy. : In this prospective interventional case series, we analyzed for one Methods year 80 consecutive primary open angle glaucoma patients who underwent mitomycin-augmented trabeculectomy. Bleb morphology was scored using the Indiana bleb appearance grading scale (IBAGS). Success was defined as IOP ≤15 mmHg with or without medications at 12 months. We tested for IOP and bleb morphological differences between groups, applied a multivariable regression analysis and determined the area under the receiver operating characteristic curve (AUC). : Age and gender were equally distributed (62.3±13.1 years, P=0.911). Results IOP of patients with a successful outcome did not differ from unsuccessful ones on day 1, 7 and 30 (all P≥0.2). The AUC of IOP at day 1, day 7 and 30 for predicting a successful outcome was 0.355, 0.452, and 0.80, respectively. The AUC for bleb morphology parameters, bleb height, extension, and vascularization, on day 14 were 0.368, 0.408, and 0.549, respectively. Values for day 30 were 0.428, 0.563, and 0.654. IOP change from day 1 to day 30 was a good predictor of failure (AUC=0.838, 95% CI: 0.704 to 0.971) with a change of more than 3 mmHg predicting failure with a sensitivity of 82.5% (95% CI: 68 to 91%) and a specificity of 87.5% (95% CI: 53 to 98%). : The postoperative IOP on day 30 had a fair to good accuracy Conclusions while the bleb features failed to predict a successful outcome. An IOP increase by as little as more than 3 mmHg during the first 30 days was a good predictor of failure. 1,2 3 1
منابع مشابه
Predictive value of early postoperative IOP and bleb morphology
Our aim was to determine the predictive value of postoperative Background bleb morphological features and intraocular pressure (IOP) on the success rate of trabeculectomy. : In this prospective interventional case series, we analyzed for one Methods year 80 consecutive primary open angle glaucoma patients who underwent mitomycin-augmented trabeculectomy. Bleb morphology was scored using the Ind...
متن کاملPredictive value of early postoperative IOP and bleb morphology
Our aim was to determine the predictive value of postoperative Background bleb morphological features and intraocular pressure (IOP) on the success rate of trabeculectomy. : In this prospective interventional case series, we analyzed for one Methods year 80 consecutive primary open angle glaucoma patients who underwent mitomycin-augmented trabeculectomy. Bleb morphology was scored using the Ind...
متن کاملPredictive value of early postoperative IOP and bleb
To determine the predictive value of postoperative bleb Background morphological features and intraocular pressure (IOP) on the success rate of trabeculectomy. : In this prospective interventional case series, we analyzed for one Methods year 80 consecutive primary open angle glaucoma patients who underwent mitomycin-augmented trabeculectomy. Bleb morphology was scored using the Indiana bleb ap...
متن کاملPredictive value of early postoperative IOP and bleb morphology in Mitomycin-C augmented trabeculectomy
Background: Our aim was to determine the predictive value of postoperative bleb morphological features and intraocular pressure (IOP) on the success rate of trabeculectomy. Methods: In this prospective interventional case series, we analyzed for one year 80 consecutive primary open angle glaucoma patients who underwent mitomycin-augmented trabeculectomy. Bleb morphology was scored using the Ind...
متن کاملAppraisal of Bleb Using Trio of Intraocular Pressure, Morphology on Slit Lamp, and Gonioscopy
PURPOSE The aim of this study was to assess bleb function using Wuerzburg bleb classification score (WBCS) for bleb morphology on slit lamp, intraocular pressure (IOP), and gonioscopy. METHODS A total of randomly selected 30 eyes posttrabeculectomy were assessed for bleb function with the trio of bleb morphology, IOP, and gonioscopy. Bleb was assessed using the WBCS of 0-12 on slit lamp, IOP ...
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